Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration.Acute radiation\ndermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the\nonset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma\nwho experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered.
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